Substance

Nilotinib

Brand name:
Tasigna

Description

 
Chemotherapy
 
Tasigna effectively inhibits the tyrosine kinase activity of the BCR-ABL oncoprotein of cell lines and leukemia cells primarily positive on the Philadelphia chromosome
Brands:
Tasigna
Availability:
Prescription needed
Pregnancy:
Consult a doctor
Alcohol:
Not detected with light alcohol consumption
Side Effects:
Clay-colored Stools, Increased Thirst, Dark Urine
Interactions:
Bone Marrow Suppression, Sprycel (dasatinib), Atorvastatin
For informational purposes only. Consult your local medical authority for advice.

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Nilotinib side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Contact your doctor right away or get emergency medical help if you have symptoms of a serious heart problem: fast or pounding heartbeats and sudden dizziness (like you might pass out).
Call your doctor at once if you have:

  • unusual bleeding (bruises, blood in your urine or stools);
  • swelling, rapid weight gain, feeling short of breath;
  • bleeding in the brain--sudden headache, confusion, vision problems, and dizziness;
  • signs of liver or pancreas problems--upper stomach pain (that may spread to your back), nausea or vomiting, dark urine, jaundice (yellowing of the skin or eyes);
  • low blood cell counts--fever, chills, night sweats, mouth sores, pale skin, unusual weakness;
  • signs of decreased blood flow--leg pain or cold feeling, chest pain, numbness, trouble walking, speech problems; or
  • signs of tumor cell breakdown--confusion, weakness, muscle cramps, nausea, vomiting, fast or slow heart rate, decreased urination, tingling in your hands and feet or around your mouth.

Nilotinib can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using nilotinib.
Common side effects may include:

  • nausea, vomiting, diarrhea, constipation;
  • rash, temporary hair loss;
  • night sweats;
  • pain in your bones, spine, joints, or muscles;
  • headache, feeling tired; or
  • runny or stuffy nose, sneezing, cough, sore throat.

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